Single-cell analysis identifies a VIM+ glioma stem-like vascular–immune state linked to myeloid OSM signaling and CEBPD activity
Background Gliomas show intertumoral and intratumoral heterogeneity, and isocitrate dehydrogenase (IDH) status is linked to biological behavior and clinical aggressiveness. Evidence suggests glioma progression depends on reciprocal crosstalk between glioma stem-like tumor cells (GSTCs) and the tumor microenvironment, w...