Author

Jian-Wei Zhang

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Open access Aug 2026

Self-supervised Small Vessel Segmentation with Shape-aware Geometric Models and Attention

This work proposes a generalized and explicit small vessel representation and presents a novel self-supervised small vessel segmentation network termed S3U-Net, which is applied to 7-Tesla brain images from elderly adults and demonstrates the successful detection of significant associations between small vessel density...

Zhiwei Deng, Songnan Xu, Jian-Wei Zhang et al. · Medical Image Analysis · 0 citations

Review Aug 2026

AI-powered medicinal chemistry and translational drug development.

This review examines how machine learning, deep learning, natural language processing (NLP), and generative modeling are being applied across medicinal chemistry and drug development, and highlights how multimodal data fusion, predictive modeling, and human-AI collaborative frameworks are supporting more informed decis...

Kaicheng U, Sophia Meixuan Zhang, Ziyu Yu et al. · Chemical Society Reviews · 0 citations