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Open access Sep 2026

RIPK3 acts as a molecular switch between neuroprotection and neuropathology during herpes simplex encephalitis

Herpes simplex virus type 1 (HSV-1) is the leading cause of sporadic viral encephalitis, where uncontrolled viral replication and neuroinflammation drive fatal brain injury. Inherited RIPK3 deficiency predisposes humans to severe disease, but the protective mechanism remains unclear. Using single-cell transcriptomics,...

Shu-Qi Wang, Jian Wang, Madison Hicks et al. · 0 citations

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