Author

Jian-Sheng Lu

h-index 10 View on Semantic Scholar

We have 2 of 43 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Sep 2026

Development and Humanization of a Camelid-Derived Neutralizing Nanobody Targeting Botulinum Neurotoxin Type A

Purpose Botulinum neurotoxin (BoNT), produced by Clostridium botulinum, is one of the most potent neurotoxins, causing botulism, a potentially fatal paralytic disease. Among different serotypes, BoNT/A is the most potent and the primary cause of botulism. The receptor-binding domain (Hc) of BoNT is crucial for targetin...

Yu-Jia Jiang, Wen-Wen Xin, Jian-Sheng Lu et al. · International Journal of Nan... · 0 citations

#protein folding Aug 2026

Oligomerized receptor binding domain blocks pan-sarbecovirus infection via enhanced avidity to host receptor.

HRBD demonstrated potent and broad-spectrum inhibition against Pangolin-CoV, SARS-CoV, SARS-CoV, SARS-CoV-2, and its variants, lowering the half-maximal inhibitory concentration (IC50) by approximately 1000-fold compared to the monomeric RBD.

Jintao Zou, Lingyu Su, Jian-Sheng Lu et al. · Antiviral Research · 0 citations