Open access
Oct 2026
Lactobacillus helveticus R0052 Ameliorates Cholestasis with FXR-Related Pathways and Modulation of Gut Microbiota
Cholestasis is an important clinical manifestation of primary sclerosing cholangitis (PSC), leading to liver injury, fibrosis and liver failure. The gut microbiota influences the pathogenesis of cholestatic liver disease by modulating metabolic and immune responses. Our study established a PSC mouse model with a 0.1% 3...
Xue-Yang Chen, Li Jiang, Ai-Ling Li et al.
· Microorganisms · 0 citations