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Jian Ma

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Open access Sep 2026

A late-stage multi-dimensional intervention rescues lethal viral pneumonia in an aged hamster model

This study initiated a multidimensional combination therapy of dexamethasone, heparin and the broad-spectrum viral decoy CoVR-MV at three days after infection and resulted in a potent reduction of high mortality, body weight loss, viral load, lung pathology and cytokine storm.

Ming Zhou, Xuan Liu, Jin-Xin Miao et al. · 0 citations
Open access Sep 2026

An Engineered Spike Immunogen Drives Broad Protection of a Bivalent Recombinant Protein COVID-19 Vaccine in Animal Models

The continued evolution of SARS-CoV-2 has reduced the protective effectiveness of first-generation vaccines and underscores the need for broadly reactive next-generation vaccine candidates. Here, we evaluated STFKB, an alum-adjuvanted bivalent recombinant protein vaccine composed of the monomeric Spike (STFKprototype)...

Zi-Kang Wang, Jia-Hua Gao, Ru Bai et al. · 0 citations

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