Author

Jian-Lin Xu

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Sep 2026

Echinococcus granulosus antigen 5: a novel immunomodulator that targets NF-κB signaling to suppress inflammation in THP-1 monocyte.

Chronic infection by Echinococcus granulosus leads to the establishment of fluid-filled cysts (hydatid cysts) in the liver or lungs of infected hosts, which can escape destruction by the host immune system for long periods. Ag5 is abundantly expressed in the cyst fluid of the fine-grained E. granulosus and plays an imp...

Fan Zhang, Zhi Li, Jian-Lin Xu et al. · International Immunopharmaco... · 0 citations

Open access Jul 2026

RNF220 safeguards meiotic synapsis and male fertility by antagonizing SYCE1 ubiquitination

The essential role of RNF220 is defined and novel molecular insights into the pathogenesis of male infertility are provided and provide novel molecular insights into the pathogenesis of male infertility.

Jing-Mei Cha, Huijuan Lin, Yingqian Xia et al. · Cell Death & Disease · 0 citations