Author

Jian-Lin Shen

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Open access Jul 2026

OsteoRAG: Retrieval-augmented generation for evidence-based osteoporosis knowledge management

The exponential growth of biomedical literature poses significant challenges for knowledge management in specialized domains such as osteoporosis. While Large Language Models (LLMs) offer advanced natural language understanding capabilities, their direct application in high-risk medical contexts is hindered by hallucin...

Xiao-Yu Xu, Jian-Lin Shen · Science in progress · 0 citations

Review Open access Aug 2026

Transcriptome-based profiling of programmed cell death signatures identifies two osteoarthritis subtypes and the hub gene DNM1L

Background Osteoarthritis (OA) poses a significant global health risk, with programmed cell death (PCD) playing a key role in its development. Methods This study utilized integrated bioinformatics tools to discover new biomarkers and therapeutic targets for OA. A comprehensive set of 1,254 PCD-related genes encompassin...

Xiao-Ning Lin, Yu-Jian Lan, Xuan Lin et al. · Frontiers in Immunology · 0 citations