Biotransformation of lithocholic acid by Mucor racemosus and the anti-neuroinflammatory activity of products.
The biotransformation of lithocholic acid (LCA) by Mucor racemosus CGMCC 3.20 resulted in the formation of four novel derivatives (compounds 1-4), characterised by 6β and/or 12β hydroxylation and acetylation, in addition to four previously recognised compounds. Comprehensive structural characterisation was achieved thr...