Anticholinergic Drug Burden and Postoperative Delirium: A Systematic Review and Meta-Analysis.
INTRODUCTION Postoperative delirium (POD) is an important postoperative neurocognitive complication, and cumulative anticholinergic drug burden (ADB) may increase its risk by impairing central cholinergic neurotransmission. This systematic review and meta-analysis aimed to clarify the overall association between ADB sc...