C3aR inhibition alleviates cerebral ischemia-reperfusion injury via STING-mediated ferroptosis through SLC7A11/GPX4
Summary Cerebral ischemia-reperfusion injury couples complement activation with innate immune signaling and ferroptotic lipid peroxidation. We investigated whether C3aR signaling modulates stimulator of interferon genes (STING)-associated ferroptosis through the solute carrier family 7 member 11 (SLC7A11)/glutathione p...