Unraveling shared immunotoxicological mechanisms linking exposure to PPCPs with Alzheimer's disease and atherosclerosis: integrative multi-omics, network toxicology, and experimental validation.
To explore how exposure to PPCPs may contribute to AD-AS comorbidity through shared immune-toxicology mechanisms, and to identify natural compounds as candidate interventions against prioritized disease-relevant targets, integrated AD and AS bulk transcriptomic datasets were integrated.