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Author

Jian-Kai Fang

2 papers indexed here

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Review Open access Sep 2026

Spatiotemporal Immune-Fibroblast Crosstalk in Pulmonary Fibrosis: From Failed Repair to Fibrotic Niche Formation

Pulmonary fibrosis is a common and often fatal outcome of fibrosing interstitial lung diseases, characterized by progressive extracellular matrix deposition, destruction of alveolar architecture and irreversible loss of respiratory function. Although fibroblast activation and epithelial dysfunction are central to disea...

Si-Meng Lu, Wei-Jia Zhang, Xiao-Ming Zhao et al. · 0 citations
Open access Sep 2026

Targeting NAMPT restrains inflammatory macrophage metabolism and attenuates acute lung injury

Nicotinamide phosphoribosyltransferase (NAMPT)-dependent NAD⁺ salvage is identified as an important regulator of inflammatory macrophage function in acute lung injury and temporally restricted, cell-selective NAMPT targeting is supported as a potential strategy for acute inflammatory lung injury.

Wei-Jia Zhang, Si-Meng Lu, Guo-Fu Sun et al. · 0 citations

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