Punicalin targets RSV glycoprotein and fusion protein at non-overlapping sites to prevent viral escape.
In RSV-infected mice, nebulized PUN provides sustained respiratory exposure, reduces lung viral loads and pathology, and attenuates inflammatory responses, and in RSV-infected mice, nebulized PUN provides sustained respiratory exposure, reduces lung viral loads and pathology, and attenuates inflammatory responses.
Ying-Cai Xiong, Jingyi Ming, Zhao-Wei Zhang et al.
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