Sep 2026
Non-canonical modulation of mitochondrial ROS and dynamics by Netrin-3 drives inflammasome activation in cardiomyocytes.
Observations support a model in which Netrin-3 participates in coupling inflammasome signaling to mitochondrial alterations through a ROS-dependent route, and whether Netrin-3 inhibition has therapeutic value in heart failure warrants further investigation.
Biao Li, Hao-Yang Ge, Xi-Wei Chen et al.
· International Immunopharmaco... · 0 citations