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Author

Jian Huang

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Open access Jul 2026

Unveiling the molecular and immune heterogeneity across distinct disease activity states of systemic lupus erythematosus through integrative bulk and single-cell transcriptomics

Abstract Objective Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterised by substantial variability in clinical presentations and disease severity. This study aims to investigate the molecular and cellular mechanisms underlying distinct SLE Disease Activity Index (SLEDAI)-defined disease stat...

Chen Shen, Ming-Zhe Guo, Jian Huang et al. · 0 citations

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