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Author

Jian-Hua Li

2 papers indexed here

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Open access Sep 2026

Engineered bacterial outer membrane vesicle vaccine prevents T cell exhaustion for antibacterial immunotherapy.

Gram-negative pathogens evade immune clearance and promote chronic infections by residing intracellularly. While outer membrane vesicles (OMVs) hold promise as antibacterial vaccine platforms, their clinical potential is limited by lysosomal entrapment of antigens and endotoxin-induced toxicity. Herein, we present an i...

Zhi-Bang Li, Ying Wang, Zhi-Yan Zhou et al. · 0 citations
Aug 2026

Zwitterionic PEGylation of Nanodrugs for Reduced Immunogenicity and Improved Drug Delivery Efficacy.

PEGylated liposomes are widely used as drug delivery carriers due to their prolonged circulation and enhanced accumulation at pathological sites. However, repeated administration can trigger the accelerated blood clearance (ABC) phenomenon, reducing delivery efficacy. Herein, we report a zwitterionic PEGylation strateg...

Ning Wang, Zhi-Liang Gao, Meng-Qi Li et al. · 0 citations

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