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Author

Jian-Di Li

3 papers indexed here

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Open access Oct 2026

TOMM5 is associated with oral cancer progression: a multi-omics analysis from single-cell atlas to in vitro validation

Abstract Aims Translocase of Outer Mitochondrial Membrane 5 (TOMM5), a mitochondrial outer membrane translocase subunit implicated in tumorigenesis, remains unexplored in oral cancer. Herein, we aimed to decipher the role of TOMM5 in oral cancer. Methods This study comprehensively explored the expression profile, clini...

Li Gao, Jian-Di Li, Yi-Yang Chen et al. · 0 citations
Open access Aug 2026

CRISPR Screen Reveals Pathways and Factors Driving Tyrosine Kinase Inhibitor Resistance in Hepatocellular Carcinoma

This study identified GPATCH4, CCT3, C19orf53, UACA, PPM1M, and LIN37 as key genes mediating TKI resistance in HCC, and identified Ferroptosis, epithelial‐mesenchymal transition and hypoxia were new research directions, which were closely related to the pathways investigated in this study.

Siyi Chen, Li-Hua Yang, Zi-Qian Liang et al. · 0 citations
Open access Jan 2026

A Potential miR‐1246‐5p–H3K27ac–NOL12 Regulatory Axis and Its Putative Tumour‐Promoting Function in Hepatocellular Carcinoma

NOL12 may be regulated by the putative miR‐1246‐5p/H3K27ac enhancer axis and promotes HCC progression through the spliceosome pathway, supporting its potential as a novel therapeutic target for HCC.

Li Xiao, Yu-Long Deng, Li-Na Liang et al. · 0 citations

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