Jian Chen

Untargeted metabolomics reveals remodeling of hepatic metabolic networks and potential tumor-associated metabolic signatures induced by ALV-J in Luhua chickens

Avian leukosis virus subgroup J (ALV-J) represents a major pathogen that severely threatens the poultry industry. The liver contains abundant sinusoidal blood vessels with slow blood flow, which facilitates the enrichment and replication of viral particles; it serves as the primary target organ of ALV-J and the site wi...