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Author

Jian Chen

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Aug 2026

Microglial RIOK3 promotes post-ischemic neuroinflammation by facilitating YBX1 phosphorylation and nuclear accumulation.

Microglia-targeted RIOK3 knockdown reduced infarct volume, improved early neurological and sensorimotor outcomes, preserved microglial process complexity, and reduced post-ischemic inflammation, and highlight the RIOK-YBX1 axis as a potential therapeutic target for ischemic stroke.

Yang Geng, Ningning Zong, Chao Zhou et al. · 0 citations

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