Clinical gradient and predictors for stepwise resistance escalation of carbapenem-susceptible, carbapenem-resistant, and difficult-to-treat resistant Pseudomonas aeruginosa infections: a 6-year retrospective cohort study
Objective Difficult-to-treat resistant Pseudomonas aeruginosa (DTR-PA) represents the most severe antimicrobial resistance phenotype of P. aeruginosa, with limited therapeutic options and poor clinical outcomes. However, previous studies have largely focused on carbapenem-resistant P. aeruginosa (CRPA), and the factors...