Integrated multi-omics, single-cell and spatial transcriptomic analyses identify an HK2/S100A2/GALNT5-associated epithelial/ductal-like program in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is characterized by marked molecular and epithelial heterogeneity, but the cross-cohort and cellular context of candidate genes remains incompletely resolved. We integrated bulk transcriptomic and proteomic data with patient-grouped machine-learning assessment, independent-cohort...
Zeyang Fan, Letian Ren, Yongqing Zhao et al.
· Discover Oncology · 0 citations