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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Jiajun He

University of Cambridge

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Open access Jul 2026

De Novo Design of Protein Switches with Diffusion-Based Ensemble Sampling

Diff-Switch is introduced, a framework for sampling switch-like backbone ensembles from pretrained protein diffusion models that preserves local domain geometry while encouraging diversity in global domain arrangements along user-specified collective variables, inspired by metadynamics.

Alireza Omidi, Jiajun He, Jennifer M. Bui et al. · 0 citations

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