Open access
Jul 2026
Exploratory Genome and Transcriptome-Wide Association Analyses of Addiction-Related Phenotypes in a Twin Cohort
The findings support a model of shared genetic liability across diverse substance use behaviors, mediated by specific gene expression patterns in the mesolimbic dopamine system and frontal cortex, and provides critical insights into the tissue-specific neurobiological pathways underlying addiction vulnerability.
Jiahua Zhou, An-Phuc Ta, Catherine Yang et al.
· Biomedicines · 0 citations