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Jiahao Zhang

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Open access Jul 2026

Metabolic reprogramming via SIRT2-deficient microglial large extracellular vesicles ameliorates alzheimer's pathology.

LEVs are identified as a critical vesicle subtype mediating the effects of SIRT2 knockdown and support a cell-free therapeutic strategy for AD centered on EVs-driven metabolic reprogramming of microglia.

Xiaolu Tang, Rui Chen, Jiawei Xing et al. · 0 citations

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