Author

Jia-Zheng Pei

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Sep 2026

UniCure: A multi-modal model for predicting personalized cancer therapy response.

UniCure is presented, a multi-modal model that combines biological and chemical foundation models to predict drug-induced transcriptomic responses across diverse cell and tissue contexts, enabling individualized drug ranking.

Ze-Xi Chen, Saisai Tian, Jia-Zheng Pei et al. · Cancer Cell · 0 citations

Aug 2026

The Multimodal Pretraining Framework CarHE Predicts Spatial Transcriptomics in Tumors from Routine Pathology Images.

CarHE (contrastive alignment of gene expression for hematoxylin and eosin images), a multimodal pretraining framework that infers high-dimensional spatial transcriptomic profiles from routine H&E-stained slides, provides a cost-effective and scalable framework for H&E-based spatial inference, supporting further validat...

Jiawei Zou, Kai Xiao, Ze-Xi Chen et al. · Cancer Research · 0 citations