Sep 2026
Abstract B012: Pan-RAS Inhibition Reprograms T Cell Immunity within the Pancreatic Adaptive Immune Microenvironment
The advent of pan-RAS and allele-specific inhibitors in clinical trials have created an urgent need to understand how RAS inhibition remodels the pancreatic immune microenvironment and alters anti-tumor immunity, to guide rational combinations with immunotherapy. We used a murine model with pancreas-specif...
Rashmi J. Kumar, E. Lasse-Opsahl, Lauren Gerbereux et al.
· Cancer Research · 0 citations