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Jia-Yi Tao

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Open access Oct 2026

Temporal Single-Nucleus Transcriptomics Defines PPARα/CPT1A-Associated Metabolic Reprogramming During Proximal Tubular Injury and Repair

Background: Metabolic reprogramming and mitochondrial dysfunction are central features of acute kidney injury (AKI), yet their temporal relationship with proximal tubular cell-state remodeling remains incompletely understood. This study aimed to characterize early metabolic alterations and proximal tubular cell-state c...

Tao Xu, Pei-Han Wang, Qi Liu et al. · 0 citations

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