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Jia-Yi Li

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Aug 2026

TvTPPIMI: A Boundary-Aware Dual-View Framework for Predicting PPI-Modulator Interactions.

Protein-protein interactions (PPIs) regulate essential cellular processes and represent an important class of therapeutic targets; however, discovering effective modulators of PPIs remains a formidable challenge. Although deep learning approaches have been widely explored for PPI modulator discovery, many rely on simpl...

Lai-Ying Yang, Jing Chen, Hong Tan et al. · 0 citations
Open access Aug 2026

Molecular Origin of the Enhanced PET Degradation Activity of LCC-ICCG Revealed by Computational Modeling

Poly(ethylene terephthalate) (PET) hydrolases have emerged as promising biocatalysts for closed-loop plastic recycling. Among the most efficient enzymes reported to date, LCC-ICCG exhibits exceptional PET-depolymerization performance under industrially relevant conditions. However, the molecular basis for its superior...

Changyi Li, Dong-Qing Wei, Wei-Yun Miao et al. · 0 citations

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