Regulation–Metabolism Rewiring Enables Efficient Nicotinamide Mononucleotide Biosynthesis in Food-Grade Lactiplantibacillus plantarum
Nicotinamide mononucleotide (NMN) is a high-value functional ingredient, yet its efficient biosynthesis in food-grade microorganisms remains limited by an incomplete understanding of regulatory mechanisms. Here, we identified a GntR-family transcription factor (TFs), lp_0262, as a key regulator of NMN metabolism in L...