Review
Open access
Jul 2026
Obesity-induced metabolic reprogramming of the tumor immune microenvironment: mechanisms, spatial niches, and immunotherapy response
Therapeutic strategies combining metabolic modulation, ICB, lifestyle intervention, and microbiota-targeted therapies may convert obesity-driven immune suppression into actionable vulnerabilities and inform combination immunotherapy strategies in obesity-associated cancers.
Yikang Xu, Jia-Xing Yang
· Frontiers in Immunology · 0 citations