Author

Jia-Xin Tian

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Open access Sep 2026

Development and evaluation of a two-tube multiplex real-time PCR assay for differential detection of Monkeypox virus clades Ia, Ib, IIa, and IIb

Monkeypox virus (MPXV) has caused two Public Health Emergencies of International Concern since 2022, with co-circulation of distinct clades (Ia, Ib, IIa, IIb) that differ in virulence and transmission patterns. Rapid discrimination of these clades is critical for outbreak control and clinical management. Here, we devel...

Xiang-Yu Zhu, Ning Shi, Yong Liu et al. · Frontiers in Microbiology · 0 citations

Aug 2026

ROS-responsive hydrogel nanoarmor enables stepwise photodynamic viral inactivation and sustained anti-inflammation for monkeypox therapy.

In mouse, rabbit, and non-human primate models with MPXV-induced skin damage, this hydrogel nanoparticle protective layer significantly inhibits viral replication and accelerates wound healing, representing a transformative, convertible platform for treating MPXV and other highly inflammatory viral infections.

Ning Shi, Xinyu Cao, Xiaolong Zhu et al. · Biomaterials · 1 citation