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Jia-Xin Qin

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Oct 2026

Targeting activated hepatic stellate cells through ferroptosis: phenethyl isothiocyanate attenuates CCl4-induced liver fibrosis by regulating iron metabolism, redox homeostasis, and autophagy.

It is shown that PEITC alleviates liver fibrosis by promoting ferroptosis-related processes in activated HSCs, mainly through the NCOA4/FTH1 axis, positioning it as a promising nutraceutical candidate for antifibrotic therapy.

Meng-Xue Sun, Jia-Xin Qin, Yuan-Fen Xie et al. · 0 citations

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