Oct 2026
Targeting activated hepatic stellate cells through ferroptosis: phenethyl isothiocyanate attenuates CCl4-induced liver fibrosis by regulating iron metabolism, redox homeostasis, and autophagy.
It is shown that PEITC alleviates liver fibrosis by promoting ferroptosis-related processes in activated HSCs, mainly through the NCOA4/FTH1 axis, positioning it as a promising nutraceutical candidate for antifibrotic therapy.
Meng-Xue Sun, Jia-Xin Qin, Yuan-Fen Xie et al.
· Food & Function · 0 citations