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Jia-Xiang Fu

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Open access Aug 2026

Pseudorabies virus pUL40 drives inflammatory signaling through competitive hijacking of EphA2 from the Akt–EphA2 interaction

These findings reveal a proviral strategy whereby PRV UL40 hijacks EphA2 to counteract an intrinsic Akt-dependent inhibitory pathway, and EphA2 S897 represents a potential therapeutic target for mitigating alphaherpesvirus immunopathology.

Yutong Tian, Hang Yin, Jia-Xiang Fu et al. · 0 citations

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