Open access
Aug 2026
Involvement of HOXA3 and chaperone-mediated autophagy in DEHP-induced ferroptosis of mouse Leydig cells via regulating GPX4 expression
Impaired Leydig cell function leads to low testosterone levels, which is associated with male reproductive developmental defects and functional disorders. Exposure to di(2-ethylhexyl) phthalate (DEHP), an endocrine-disrupting chemical, can cause damage to Leydig cells, yet the underlying mechanism remains unclear....
Yan-Yan Liu, C. Guan, Lin-Ling Xu et al.
· Cell Death & Disease · 0 citations