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Jia-Xi Qiao

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#protein folding Review Open access Oct 2026

Endoplasmic reticulum stress in autoimmune skin diseases: immune activation, cutaneous cell damage, and therapeutic advances

Endoplasmic reticulum stress (ERS) arises when the protein-folding load, or perturbations in calcium and redox homeostasis, outpace the adaptive capacity of the endoplasmic reticulum (ER). The unfolded protein response (UPR) initially reduces secretory load and restores proteostasis. Persistent stress can redirect the...

Jia-Xi Qiao, Jia Chen, Jin-Bo Chen et al. · 0 citations

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