ABSTRACT Aims To systematically characterize the genetic landscape of dystonia in a Mainland Chinese cohort, where over 60% of patients currently lack a molecular diagnosis due to limited large‐scale genomic studies. Methods Whole‐exome sequencing (WES) was performed in a cohort of 147 clinically diagnosed dystonia pat...
This study aimed to quantify recent trends in the HIV burden, the magnitude of the HIV burden associated with IPV, and the potential impact of declining financial support globally, and to estimate how funding levels could affect antiretroviral therapy (ART) coverage.
A. Carter, Meixin Zhang, B. Trejo et al.· The Lancet HIV· 1 citation
This review integrates core macrophage immunometabolic pathways with TAM biology, emphasizing how lactate accumulation, altered lipid mediators, cholesterol remodeling, and amino acid dependencies reshape macrophage states and suppress antitumor immunity through checkpoint signaling and metabolic deprivation.
Jia-Wei He, Bo-Wen Wang, En-Ze Lei et al.· Frontiers in Immunology· 0 citations
The authors' findings provide genetic evidence suggesting a potential association between PFAS exposure and RA risk, and mechanistic studies are warranted to elucidate the biological pathways underlying the potential relationship between PFAS exposure and RA.
