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Jia-Qing Guo

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Open access Sep 2026

Label-free two-photon fluorescence lifetime imaging of FADH2 for rapid diagnosis and grading of glioma

Abstract. Significance Glioma diagnosis currently relies on histopathology, which provides essential morphological information but fails to capture the dynamic metabolic heterogeneity underlying tumor progression. Aim This study seeks to establish a label-free fluorescence lifetime imaging strategy to characterize the...

Shi-Qi Wang, Yi-Xuan Yang, Chao-Dong Yin et al. · 0 citations
#explainable ai Open access Sep 2026

Explainable AI-Assisted Label-Free Raman Biosensing Reveals Therapy-Associated Spectral Signatures in Melanoma Tumors

Raman spectroscopy integrated with explainable machine learning provides a sensitive, label-free method for distinguishing treatment-associated spectral differences among melanoma tissues, and may serve as a complementary spectroscopic tool alongside conventional histological and molecular analyses for investigating tr...

Muhammad Nouman Khan, Qing-Song Zhou, Jia-Qing Guo et al. · 0 citations

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