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Jia-Qi Sun

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Open access Oct 2026

MTR4: A Conserved Youth Factor for Vascular Endothelium.

Vascular endothelial cell (VEC) senescence drives organismal aging and age-related pathologies, yet the intrinsic factors preserving endothelial youthfulness remain poorly defined. Here, we identify MTR4, an evolutionarily conserved RNA helicase and nuclear RNA exosome cofactor, as a novel regulator of VEC senescence....

Zhen-Yuan Guo, Zhi-Qiang Chen, Jia-Qi Sun et al. · 0 citations

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