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Review Open access 2026

Lung xenotransplantation: From the first human milestone to the path of clinical translation

Lung transplantation remains the only curative treatment for end-stage lung diseases, yet a critical shortage of donor organs persists. Xenotransplantation using genetically modified pigs has emerged as a promising solution, with recent breakthroughs in cardiac and renal xenotransplantation demonstrating clinical feasi...

Yue-Lin Fang, Jia-Ni Gao, Minjue Shan et al. · 0 citations
Open access Sep 2026

A ROS-responsive platelet extracellular vesicle biomimetic nanosystem regulates CD36/Fyn-CXCL-NETosis pathway-mediated immune-inflammatory amplification in the treatment of transfusion-related acute lung injury

Transfusion-related acute lung injury (TRALI) remains a life-threatening complication of blood transfusion, yet the macrophage-neutrophil-NETosis inflammatory amplification mechanism and effective interventions are still incompletely defined. Here, we examined a CD36/Fyn-CXCL-related axis in TRALI and evaluated a ROS-r...

Jiani Gao, Ke Zhou, Yi-Jiu Ren et al. · 0 citations

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