Author

Jiali Yao

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#protein folding Open access Sep 2026

Multiple strategies to improve the yield of snake thrombin-like enzyme agkihpin from Gloydius halys pallas in Pichia pastoris

In our previous research, we successfully identified agkihpin, a snake venom thrombin-like enzyme (SVTLE) from Gloydius halys pallas . It possesses thrombin-like activity and exhibits multiple functions, including inhibition of tumor invasion and metastasis. Its unique enzymatic properties make agkihpin a pro...

Jia-Li Yao, Yu-Jia Yang, Wen-Jing Zhao et al. · Microbial Cell Factories · 0 citations

Open access Jul 2026

Systematic multi-parameter optimization of an injectable thermosensitive CS/β-GP/HEC hydrogel for 3D cell culture applications

Injectable thermosensitive hydrogels have been widely investigated as minimally invasive scaffolds for three-dimensional (3D) cell culture. In this study, we systematically screened a chitosan (CS)/β-glycerophosphate (β-GP)/hydroxyethyl cellulose (HEC) ternary hydrogel system using a 2 × 2 × 2 factorial design. By eval...

Wenjing Zhao, Ying Liu, Jiali Yao et al. · PLoS ONE · 0 citations