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Open access Sep 2026

Cellular senescence of fibro-adipogenic progenitors by STAT5A/GFPT2/O-GlcNAcylation impairs muscle recovery after glucocorticoid-induced injury.

The clinical use of glucocorticoids often leads to skeletal muscle injury, characterized by muscle atrophy and dysfunction. Fibro-adipogenic progenitors (FAPs) play an important role in maintaining muscle homeostasis, but their roles in the recovery of skeletal muscle after glucocorticoid-induced injury remain largely...

Bing-Fei Li, Wei Xiang, Wan-Ru Qi et al. · 0 citations
Open access Aug 2026

Dual-Target Cardiac Regeneration: Controllable Nfyb/Nr3c1 Cointervention Spurs Cardiomyocyte Cytokinesis After Myocardial Infarction.

BACKGROUND Myocardial infarction can cause a massive loss of functional cardiomyocytes, yet effective strategies to stimulate cardiac regeneration remain lacking. A key barrier to adult cardiomyocyte proliferation appears to be cytokinesis inhibition. This study aimed to determine whether combining proliferation stimul...

Bing-Jun Lu, Wujian Liu, Ziyan Ge et al. · 0 citations

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