Author

Jia-Le Yang

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Open access Sep 2026

Safety profile of entrectinib in NSCLC: Multi-source pharmacovigilance analysis using FAERS and JADER

Background Entrectinib is effective for ROS1-positive non-small cell lung cancer (NSCLC), but its postmarketing safety profile remains incompletely characterized outside clinical trials. We conducted a dual-database pharmacovigilance study to characterize real-world reporting patterns, identify cross-database replicate...

Jia-Le Yang, Jia-Wen Liu, Guan-Bo Zhao et al. · PLoS ONE · 1 citation

Open access Sep 2026

Automated whole-brain MRI segmentation combined with clinical scores for the diagnosis of sepsis-associated encephalopathy: a case-control study

Sepsis-associated encephalopathy (SAE) is a serious complication of sepsis that can lead to high mortality and poor neurological outcomes. Current diagnostic methods, whether based on clinical scores or brain images, remain inaccurate. We aimed to formulate a multimodal model that incorporated three-dimensional (...

Sha-Sha Shao, Yan-Yan Liu, Jia-Le Yang et al. · BMC Medical Imaging · 0 citations