Author

Jia-Jia Zhu

3 papers indexed here

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Open access Jan 2026

Altered Functional Connectivity and Small‐World Network Properties in MDD With Daytime Sleepiness: Implications for Anhedonia

Background Approximately 37.4% to 57.1% of people with major depressive disorder (MDD) exhibit symptoms of daytime sleepiness (DS). Patients with MDD with concurrent DS tend to have worse clinical outcomes and often experience severe anhedonia. As a key symptom of MDD, anhedonia is strongly associated with its severity...

Yi-Fei Li, Shu-Kun Zhu, Qin Hu et al. · Depression and Anxiety · 0 citations

Sep 2026

Gut microbiota correlating with glycerophospholipid metabolism dysregulation is associated with brain functional alterations in adolescent depression.

Gut microbiota dysbiosis has been linked to depression; however, evidence regarding this association in adolescents remains scarce, and the underlying molecular and neuropathological mechanisms are poorly understood. We conducted an integrative multi-omics study combining fecal metagenomic sequencing, serum untargeted...

Jia-Yi Tian, Ying-Xue Wang, Lili Lu et al. · Brain, behavior, and immunit... · 0 citations

Open access Sep 2026

Characterizing the role of the gut microbiota-inflammation-brain axis in major depressive disorder: an integrative multi-omics study.

BACKGROUND Gut microbial dysbiosis and inflammation have been implicated in the pathophysiology of major depressive disorder (MDD). However, no attempts have been made to comprehensively investigate the potential relationship between gut microbiota, inflammation, brain function, and clinical features in MDD. METHODS...

Wenming Zhao, Dao-Min Zhu, Xu-Feng Zhao et al. · NeuroImage · 0 citations