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Author

Jia-Jia Li

2 papers indexed here

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Open access Sep 2026

High‐throughput identification of carboxylate‐free ligands for the E3 ligase Kelch domain‐containing protein 2

It is demonstrated that KLHDC2 can accommodate non-carboxylate scaffolds and expands the chemical space for developing KLHDC2-based targeted protein degradation strategies and expands the chemical space for developing KLHDC2-based targeted protein degradation strategies.

Yao Chen, Rui-Chen Gao, Jia-Jia Li et al. · 0 citations
#protein folding Open access Sep 2026

Consensus design and in silico screening of GH42 β-galactosidase for enhanced catalytic hydrolysis of whey lactose.

This study addresses a major bottleneck in dairy waste management by engineering a highly efficient, thermophilic enzyme for lactose hydrolysis, transforming the cheese manufacturing by-product whey into a high-value resource. While traditional glycoside hydrolase family 2 (GH2) enzymes suffer from poor industrial ther...

Si-Meng Ding, Jia-Jia Li, Jia-Hui Li et al. · 0 citations

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