Jia-Jia Duan

Multi-omics profiling reveals microbiota–gut–brain axis dysregulation in an LPS-induced model of sepsis-associated encephalopathy

Background Sepsis-associated encephalopathy (SAE) is a common complication of sepsis. Its underlying mechanisms remain incompletely understood, and effective treatments are still lacking. Recent studies have shown that the microbiota-gut-brain axis may play a key role in the pathogenesis of SAE, but its potential mecha...