Swine influenza virus (SIV) poses a continuous threat to global pig production and public health. Efficient SIV replication is highly dependent on host factors, making their identification and functional characterization important for the development of host-directed antiviral strategies. Here, we investigated the role...
Hui-Min Sun, Di-Dan Luo, Shao-Yu Tu et al.· Microbiology Research· 0 citations
It is demonstrated that the viral nucleoprotein (NP) harnesses the host transcriptional corepressor TLE1 to enhance viral polymerase activity while suppressing the cellular innate response.
Xiaomeng Yang, Haoran Sun, Peng Luo et al.· Molecules and Cells· 0 citations
The structure of PEDV HNXX-strain spike domain B (S1B) is determined and a strain-specific vulnerable site on the PEDV S-trimer is identified, providing insight into how cell-surface membrane fusion activity may influence viral entry pathway selection and antibody neutralization efficacy.
Jian-Bo Liu, Sheng Wang, Zi-Mu Li et al.· bioRxiv· 0 citations
The findings uncover a previously unrecognized role of RBM6 in shaping influenza virus replication and highlight the RBM6-M901C axis may serve as potential targets for controlling influenza virus adaptation and interspecies transmission.
Jia-Hui Zou, Shao-Yu Tu, Hui-Min Sun et al.· bioRxiv· 0 citations
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