Respiratory diseases represent a severe global health burden. However, the clinical efficacy of conventional therapeutics is severely limited by complex pulmonary physiological barriers, including mucociliary clearance, alveolar-capillary barrier, and alveolar macrophage phagocytosis. Biomimetic nano drug delivery syst...
Shao-Huang Wu, Bingyi Lu, Hanjie Chen et al.· Journal of Controlled Releas...· 1 citation
Abstract PEGylated poly(lactic-co-glycolic acid) (PEG-PLGA) nanoparticles have attracted increasing attention as a versatile and biocompatible nanoplatform for non-small cell lung cancer (NSCLC) therapy. Benefiting from prolonged circulation time, controllable drug-release behavior, and flexible surface modification, P...
Mingyao Huang, Jia-Hui Zhang, Zhanying Hao et al.· International Journal of Nan...· 0 citations
The poliovirus receptor (CD155) is an emerging immune checkpoint molecule involved in the suppression of anti-tumor immunity. In ovarian cancer, CD155 is frequently overexpressed and interacts with receptors such as TIGIT, CD96, and CD226 to modulate the activity of T cells, NK cells, and dendritic cells. These interac...
Ming-Yao Huang, Jia-Hui Zhang, Hui-Yan Huang et al.· Frontiers in Immunology· 0 citations
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