Wenyang Xiaozheng Decoction attenuates renal fibrosis and suppresses pyroptosis-associated signaling: insights from integrated transcriptomics and serum pharmacochemistry.
ETHNOPHARMACOLOGICAL RELEVANCE Wenyang Xiaozheng Decoction (WXD) is traditionally prescribed for chronic kidney disease based on the principle of warming yang and resolving blood stasis. However, whether its anti-fibrotic effects involve inflammation-associated pyroptosis remains unclear. AIM OF THE STUDY To evaluate...