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Jia-He Zhao

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Review Open access Aug 2026

Immune Dysregulation, Compartment-Specific Biology, and Therapeutic Biomarkers in Mycosis Fungoides and Sézary Syndrome

Cutaneous T-cell lymphoma (CTCL), including mycosis fungoides (MF) and Sézary syndrome (SS), is defined by malignant CD4+ T-cell clones that evolve within and remodel the skin and systemic immune compartments. For disease biology and immune remodeling, we prioritize evidence from human primary samples; for therapeutic...

Tian-Tian Zhang, Wei-Li Xue, Si-Mo Du et al. · 0 citations
Review Open access Sep 2026

T-cell redirecting therapies in lung cancer - a comprehensive analysis of clinical trials

T cell-redirected therapy is positioned to extend the survival frontier for patients whose lung cancer has escaped existing treatments, and combination strategies pairing T cell-redirected therapies with ICIs, antibody-drug conjugates, and allogeneic or innate immune effectors represent the most promising path toward d...

Jia-He Zhao, Ayrton I. Bangolo, Li-Li Zhang et al. · 0 citations

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